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Nuclear import of high risk HPV16 E7 oncoprotein is mediated by its zinc-binding domain via hydrophobic interactions with Nup62

We previously discovered that nuclear import of high risk HPV16 E7 is mediated by a cNLS located within the zinc-binding domain via a pathway that is independent of karyopherins/importins (Angeline et al., 2003; Knapp et al., 2009). In this study we continued our characterization of the cNLS and nuc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Eberhard, Jeremy, Onder, Zeynep, Moroianu, Junona
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789256/
https://ncbi.nlm.nih.gov/pubmed/24074597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.08.017
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