Atorvastatin overcomes gefitinib resistance in KRAS mutant human non-small cell lung carcinoma cells

The exact influence of statins on gefitinib resistance in human non-small cell lung cancer (NSCLC) cells with KRAS mutation alone or KRAS/PIK3CA and KRAS/PTEN comutations remains unclear. This work found that transfection of mutant KRAS plasmids significantly suppressed the gefitinib cytotoxicity in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chen, J, Bi, H, Hou, J, Zhang, X, Zhang, C, Yue, L, Wen, X, Liu, D, Shi, H, Yuan, J, Liu, J, Liu, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789171/
https://ncbi.nlm.nih.gov/pubmed/24071646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.312
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados