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Neuronal STAT3 activation is essential for CNTF- and inflammatory stimulation-induced CNS axon regeneration

CNS neurons, such as retinal ganglion cells (RGCs), do not normally regenerate injured axons, but instead undergo apoptotic cell death. Regenerative failure is due to inhibitory factors in the myelin and forming glial scar as well as due to an insufficient intrinsic capability of mature neurons to r...

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Bibliografische gegevens
Hoofdauteurs: Leibinger, M, Andreadaki, A, Diekmann, H, Fischer, D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789169/
https://ncbi.nlm.nih.gov/pubmed/24052073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.310
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