MAL hypermethylation is a tissue-specific event that correlates with MAL mRNA expression in esophageal carcinoma

MAL promoter hypermethylation was examined in 260 human esophageal specimens using real-time quantitative methylation-specific PCR (qMSP). MAL hypermethylation showed highly discriminative ROC curve profiles which clearly distinguished esophageal adenocarcinomas (EAC) from both esophageal squamous c...

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Autores principales: Jin, Zhe, Wang, Liang, Zhang, Yuan, Cheng, Yulan, Gao, Yan, Feng, Xianling, Dong, Ming, Cao, Ziyi, Chen, Si, Yu, Huimin, Zhao, Zhenfu, Zhang, Xiaojing, Liu, Jie, Mori, Yuriko, Fan, Xinmin, Meltzer, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789153/
https://ncbi.nlm.nih.gov/pubmed/24088706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02838
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