Empirical validation of viral quasispecies assembly algorithms: state-of-the-art and challenges

Next generation sequencing (NGS) is superseding Sanger technology for analysing intra-host viral populations, in terms of genome length and resolution. We introduce two new empirical validation data sets and test the available viral population assembly software. Two intra-host viral population ‘quas...

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Hauptverfasser: Prosperi, Mattia C. F., Yin, Li, Nolan, David J., Lowe, Amanda D., Goodenow, Maureen M., Salemi, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789152/
https://ncbi.nlm.nih.gov/pubmed/24089188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02837
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