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Enhanced and sustained topical ocular delivery of cyclosporine A in thermosensitive hyaluronic acid-based in situ forming microgels

For nearly a decade, thermoresponsive ophthalmic in situ gels have been recognized as an interesting and promising ocular topical delivery vehicle for lipophilic drugs. In this study, a series of thermosensitive copolymers, hyaluronic acid-g-poly(N-isopropylacrylamide) (HA-g-PNIPAAm), was synthesize...

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Detalhes bibliográficos
Main Authors: Wu, Yijun, Yao, Jing, Zhou, Jianping, Dahmani, Fatima Zohra
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788692/
https://ncbi.nlm.nih.gov/pubmed/24092975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S47665
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