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Towards Breaking the Histone Code – Bayesian Graphical Models for Histone Modifications

BACKGROUND: Histones are proteins that wrap DNA around in small spherical structures called nucleosomes. Histone modifications (HMs) refer to the post-translational modifications to the histone tails. At a particular genomic locus, each of these HMs can either be present or absent, and the combinato...

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Detalhes bibliográficos
Main Authors: Mitra, Riten, Müller, Peter, Liang, Shoudan, Xu, Yanxun, Ji, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788610/
https://ncbi.nlm.nih.gov/pubmed/23748248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.113.000100
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