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The very many faces of presenilins and the γ-secretase complex
Presenilin is a central, catalytic component of the γ-secretase complex which conducts intramembrane cleavage of various protein substrates. Although identified and mainly studied through its role in the development of amyloid plaques in Alzheimer disease, γ-secretase has many other important functi...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer Vienna
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3788181/ https://ncbi.nlm.nih.gov/pubmed/23504135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00709-013-0494-y |
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