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Influence of DNMT Genotype on Global and Site Specific DNA Methylation Patterns in Neonates and Pregnant Women

This study examines the relationship between common genetic variation within DNA methyltransferase genes and inter-individual variation in DNA methylation. Eleven polymorphisms spanning DNMT1 and DNMT3B were genotyped. Global and gene specific (IGF2, IGFBP3, ZNT5) DNA methylation was quantified by L...

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Detalhes bibliográficos
Main Authors: Potter, Catherine, McKay, Jill, Groom, Alexandra, Ford, Dianne, Coneyworth, Lisa, Mathers, John C., Relton, Caroline L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788139/
https://ncbi.nlm.nih.gov/pubmed/24098518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076506
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