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A novel Ebola virus expressing luciferase allows for rapid and quantitative testing of antivirals

Ebola virus (EBOV) causes a severe hemorrhagic fever with case fatality rates of up to 90%, for which no antiviral therapies are available. Antiviral screening is hampered by the fact that development of cytopathic effect, the easiest means to detect infection with wild-type EBOV, is relatively slow...

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Hlavní autoři: Hoenen, Thomas, Groseth, Allison, Callison, Julie, Takada, Ayato, Feldmann, Heinz
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787978/
https://ncbi.nlm.nih.gov/pubmed/23751367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.05.017
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