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Tuning voltage-gated channel activity and cellular excitability with a sphingomyelinase

Voltage-gated ion channels generate action potentials in excitable cells and help set the resting membrane potential in nonexcitable cells like lymphocytes. It has been difficult to investigate what kinds of phospholipids interact with these membrane proteins in their native environments and what fu...

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Bibliographic Details
Main Authors: Combs, David J., Shin, Hyeon-Gyu, Xu, Yanping, Ramu, Yajamana, Lu, Zhe
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787777/
https://ncbi.nlm.nih.gov/pubmed/24043861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201310986
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