Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase

G-protein activated inwardly rectifying K(+) channels (GIRKs) of the heterotetrameric GIRK1/GIRK4 composition mediate I(K + ACh) in atrium and are regulated by cAMP dependent protein kinase (PKA). Phosphorylation of GIRK1/GIRK4 complexes promotes the activation of the channel by the G-protein Gβγ-di...

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Main Authors: Treiber, Fritz, Rosker, Christian, Keren-Raifman, Tal, Steinecker, Bibiane, Gorischek, Astrid, Dascal, Nathan, Schreibmayer, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Pub. Co 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787752/
https://ncbi.nlm.nih.gov/pubmed/23305758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.12.016
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