Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states

The interaction of 18-methoxycoronaridine (18-MC) with nicotinic acetylcholine receptors (AChRs) was compared with that for ibogaine and phencyclidine (PCP). The results established that 18-MC: (a) is more potent than ibogaine and PCP inhibiting (±)-epibatidine-induced AChR Ca(2+) influx. The potenc...

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Main Authors: Arias, Hugo R., Rosenberg, Avraham, Feuerbach, Dominik, Targowska-Duda, Katarzyna M., Maciejewski, Ryszard, Jozwiak, Krzysztof, Moaddel, Ruin, Glick, Stanley D., Wainer, Irving W.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787694/
https://ncbi.nlm.nih.gov/pubmed/20303928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.03.013
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