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Extending the Serum Half-Life of G-CSF via Fusion with the Domain III of Human Serum Albumin

Protein fusion technology is one of the most commonly used methods to extend the half-life of therapeutic proteins. In this study, in order to prolong the half-life of Granulocyte colony stimulating factor (G-CSF), the domain III of human serum albumin (3DHSA) was genetically fused to the N-terminal...

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Detalhes bibliográficos
Main Authors: Zhao, Shuqiang, Zhang, Yu, Tian, Hong, Chen, Xiaofei, Cai, Di, Yao, Wenbing, Gao, Xiangdong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787585/
https://ncbi.nlm.nih.gov/pubmed/24151579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/107238
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