Chronic Cocaine Dampens Dopamine Signaling during Cocaine Intoxication and Unbalances D(1) over D(2) Receptor Signaling

Dopamine increases triggered by cocaine and consequent stimulation of dopamine receptors (including D(1) and D(2)) are associated with its rewarding effects. However, while facilitation of D(1) receptor (D(1)R) signaling enhances the rewarding effects of cocaine, facilitation of D(2)R signaling decr...

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Autores principales: Park, Kicheon, Volkow, Nora D., Pan, Yingtian, Du, Congwu
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787501/
https://ncbi.nlm.nih.gov/pubmed/24089490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1935-13.2013
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