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The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin–based motility

Vaccinia virus dissemination relies on the N-WASP–ARP2/3 pathway, which mediates actin tail formation underneath cell-associated extracellular viruses (CEVs). Here, we uncover a previously unappreciated role for the formin FHOD1 and the small GTPase Rac1 in vaccinia actin tail formation. FHOD1 deple...

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Detalhes bibliográficos
Main Authors: Alvarez, Diego E., Agaisse, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787377/
https://ncbi.nlm.nih.gov/pubmed/24062339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303055
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