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The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin–based motility
Vaccinia virus dissemination relies on the N-WASP–ARP2/3 pathway, which mediates actin tail formation underneath cell-associated extracellular viruses (CEVs). Here, we uncover a previously unappreciated role for the formin FHOD1 and the small GTPase Rac1 in vaccinia actin tail formation. FHOD1 deple...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3787377/ https://ncbi.nlm.nih.gov/pubmed/24062339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303055 |
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