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Intraperitoneal Injection of Clodronate Liposomes Eliminates Visceral Adipose Macrophages and Blocks High-fat Diet-induced Weight Gain and Development of Insulin Resistance

Macrophage infiltration in adipose tissue is strongly correlated with obesity. The exact role of macrophage in the development of obesity, however, has not been fully understood. In this study, using intraperitoneal injection of clodronate liposomes, we tissue-specifically depleted visceral adipose...

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Bibliografische gegevens
Hoofdauteurs: Bu, Le, Gao, Mingming, Qu, Shen, Liu, Dexi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787235/
https://ncbi.nlm.nih.gov/pubmed/23821353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9501-7
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