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Intraperitoneal Injection of Clodronate Liposomes Eliminates Visceral Adipose Macrophages and Blocks High-fat Diet-induced Weight Gain and Development of Insulin Resistance

Macrophage infiltration in adipose tissue is strongly correlated with obesity. The exact role of macrophage in the development of obesity, however, has not been fully understood. In this study, using intraperitoneal injection of clodronate liposomes, we tissue-specifically depleted visceral adipose...

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Detalhes bibliográficos
Main Authors: Bu, Le, Gao, Mingming, Qu, Shen, Liu, Dexi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787235/
https://ncbi.nlm.nih.gov/pubmed/23821353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9501-7
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