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Intraperitoneal Injection of Clodronate Liposomes Eliminates Visceral Adipose Macrophages and Blocks High-fat Diet-induced Weight Gain and Development of Insulin Resistance

Macrophage infiltration in adipose tissue is strongly correlated with obesity. The exact role of macrophage in the development of obesity, however, has not been fully understood. In this study, using intraperitoneal injection of clodronate liposomes, we tissue-specifically depleted visceral adipose...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Bu, Le, Gao, Mingming, Qu, Shen, Liu, Dexi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Springer US 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787235/
https://ncbi.nlm.nih.gov/pubmed/23821353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9501-7
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