Quantification of Swelling and Erosion in the Controlled Release of a Poorly Water-Soluble Drug Using Synchrotron X-ray Computed Microtomography

The hydration layer plays a key role in the controlled drug release of gel-forming matrix tablets. For poorly water-soluble drugs, matrix erosion is considered as the rate limiting step for drug release. However, few investigations have reported on the quantification of the relative importance of sw...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yin, Xianzhen, Li, Haiyan, Guo, Zhen, Wu, Li, Chen, Fangwei, de Matas, Marcel, Shao, Qun, Xiao, Tiqiao, York, Peter, He, You, Zhang, Jiwen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787229/
https://ncbi.nlm.nih.gov/pubmed/23861022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9498-y
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