Effects of Selected OATP and/or ABC Transporter Inhibitors on the Brain and Whole-Body Distribution of Glyburide

Glyburide (glibenclamide, GLB) is a widely prescribed antidiabetic with potential beneficial effects in central nervous system injury and diseases. In vitro studies show that GLB is a substrate of organic anion transporting polypeptide (OATP) and ATP-binding cassette (ABC) transporter families, whic...

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Hlavní autoři: Tournier, Nicolas, Saba, Wadad, Cisternino, Salvatore, Peyronneau, Marie-Anne, Damont, Annelaure, Goutal, Sébastien, Dubois, Albertine, Dollé, Frédéric, Scherrmann, Jean-Michel, Valette, Héric, Kuhnast, Bertrand, Bottlaender, Michel
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787228/
https://ncbi.nlm.nih.gov/pubmed/23907487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9514-2
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