Structure Activity Relationships in Alkylammonium C(12)-Gemini Surfactants Used as Dermal Permeation Enhancers

The purpose of this study was to determine the ability and the safety of a series of alkylammonium C12-gemini surfactants to act as permeation enhancers for three model drugs, namely lidocaine HCl, caffeine, and ketoprofen. In vitro permeation studies across dermatomed porcine skin were performed ov...

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Bibliografiske detaljer
Main Authors: Silva, Sérgio M. C., Sousa, João J. S., Marques, Eduardo F., Pais, Alberto A. C. C., Michniak-Kohn, Bozena B.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787226/
https://ncbi.nlm.nih.gov/pubmed/23959685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9518-y
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