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Effect of surfactants and pH on naltrexone (NTX) permeation across buccal mucosa
The objective of this pre-formulation study was to systematically investigate the effects of two surfactants (Brij 58(®) and Tween 80(®)) and change in solution pH on in vitro permeation of naltrexone HCl (NTX-HCl) across tissue engineered human buccal mucosa. For the study, 10 mg/mL solutions of Tw...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103779/ https://ncbi.nlm.nih.gov/pubmed/21443939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2011.03.046 |
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