Clonogenic Multiple Myeloma Cells have Shared stemness Signature Associated with Patient Survival

Multiple myeloma is the abnormal clonal expansion of post germinal B cells in the bone marrow. It was previously reported that clonogenic myeloma cells are CD138(−). Human MM cell lines RPMI8226 and NCI H929 contained 2-5% of CD138(−) population. In this study, we showed that CD138(−) cells have inc...

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Autors principals: Reghunathan, Renji, Bi, Chonglei, Liu, Shaw Cheng, Loong, Koh Tze, Chung, Tae-Hoon, Huang, Gaofeng, Chng, Wee Joo
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2013
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787153/
https://ncbi.nlm.nih.gov/pubmed/23985559
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