Gli1 Transcriptional Activity is Negatively Regulated by AKT2 in Neuroblastoma

Activation of the Hedgehog (Hh) signaling pathway has been implicated in a variety of malignancies including neuroblastoma. Expression of Gli1, a downstream effector of Hh, correlates with a favorable prognosis in patients with neuroblastoma. Moreover, Gli1 overexpression reduces mitotic index and i...

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Detaylı Bibliyografya
Asıl Yazarlar: Paul, Pritha, Volny, Natasha, Lee, Sora, Qiao, Jingbo, Chung, Dai H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2013
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787147/
https://ncbi.nlm.nih.gov/pubmed/23900341
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