Targeting p35/Cdk5 Signalling via CIP-Peptide Promotes Angiogenesis in Hypoxia

Cyclin-dependent kinase-5 (Cdk5) is over-expressed in both neurons and microvessels in hypoxic regions of stroke tissue and has a significant pathological role following hyper-phosphorylation leading to calpain-induced cell death. Here, we have identified a critical role of Cdk5 in cytoskeleton/foca...

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Bibliographic Details
Main Authors:	Bosutti, Alessandra, Qi, Jie, Pennucci, Roberta, Bolton, David, Matou, Sabine, Ali, Kamela, Tsai, Li-Huei, Krupinski, Jerzy, Petcu, Eugene B., Montaner, Joan, Al Baradie, Raid, Caccuri, Francesca, Caruso, Arnaldo, Alessandri, Giulio, Kumar, Shant, Rodriguez, Cristina, Martinez-Gonzalez, Jose, Slevin, Mark
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2013
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3787057/ https://ncbi.nlm.nih.gov/pubmed/24098701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075538
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Targeting p35/Cdk5 Signalling via CIP-Peptide Promotes Angiogenesis in Hypoxia

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