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Loss of Fibrinogen in Zebrafish Results in Symptoms Consistent with Human Hypofibrinogenemia
Cessation of bleeding after trauma is a necessary evolutionary vertebrate adaption for survival. One of the major pathways regulating response to hemorrhage is the coagulation cascade, which ends with the cleavage of fibrinogen to form a stable clot. Patients with low or absent fibrinogen are at ris...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3787019/ https://ncbi.nlm.nih.gov/pubmed/24098662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074682 |
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