A Three-Marker FISH Panel Detects More Genetic Aberrations of AR, PTEN and TMPRSS2/ERG in Castration-Resistant or Metastatic Prostate Cancers than in Primary Prostate Tumors

TMPRSS2/ERG rearrangement, PTEN gene deletion, and androgen receptor (AR) gene amplification have been observed in various stages of human prostate cancer. We hypothesized that using these markers as a combined panel would allow better differentiation between low-risk and high-risk prostate cancer....

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Main Authors: Qu, Xiaoyu, Randhawa, Grace, Friedman, Cynthia, Kurland, Brenda F., Glaskova, Lena, Coleman, Ilsa, Mostaghel, Elahe, Higano, Celestia S., Porter, Christopher, Vessella, Robert, Nelson, Peter S., Fang, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787014/
https://ncbi.nlm.nih.gov/pubmed/24098661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074671
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