Hypoxia Pathways and Cellular Stress Activate Pancreatic Stellate Cells: Development of an Organotypic Culture Model of Thick Slices of Normal Human Pancreas

Pancreatic stellate cells (PSC) are involved in fibrogenesis and oncogenesis by modulating the extracellular matrix. AIM: To evaluate the effect of cellular stress on PSC activation using a model of normal human pancreatic tissue slices culture preserving the microenvironment. METHODS: Thin sections...

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Detalhes bibliográficos
Main Authors: Rebours, Vinciane, Albuquerque, Miguel, Sauvanet, Alain, Ruszniewski, Philippe, Lévy, Philippe, Paradis, Valérie, Bedossa, Pierre, Couvelard, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786955/
https://ncbi.nlm.nih.gov/pubmed/24098783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076229
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