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Control of the Rescue and Replication of Semliki Forest Virus Recombinants by the Insertion of miRNA Target Sequences

Due to their broad cell- and tissue-tropism, alphavirus-based replication-competent vectors are of particular interest for anti-cancer therapy. These properties may, however, be potentially hazardous unless the virus infection is controlled. While the RNA genome of alphaviruses precludes the standar...

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Detalhes bibliográficos
Main Authors: Ratnik, Kaspar, Viru, Liane, Merits, Andres
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786945/
https://ncbi.nlm.nih.gov/pubmed/24098728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075802
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