An Updated Meta-Analysis on the Association of MDM2 SNP309 Polymorphism with Colorectal Cancer Risk

BACKGROUND: The mouse double minute 2 (MDM2) gene encodes a phosphoprotein that interacts with P53 and negatively regulates its activity. The SNP309 polymorphism (T-G) in the promoter of MDM2 gene has been reported to be associated with enhanced MDM2 expression and tumor development. Studies investi...

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Bibliografiske detaljer
Main Authors: Qin, Xue, Peng, Qiliu, Tang, Weizhong, Lao, Xianjun, Chen, Zhiping, Lai, Hao, Deng, Yan, Mo, Cuiju, Sui, Jingzhe, Wu, Junrong, Zhai, Limin, Yang, Shi, Li, Shan, Zhao, Jinmin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786895/
https://ncbi.nlm.nih.gov/pubmed/24098760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076031
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