MDM2 SNP309 accelerates colorectal tumour formation in women

Recent studies have shown that the G‐allele of MDM2 SNP309 (T/G) in the p53 tumour suppressor pathway can accelerate tumorigenesis and alter the risk of various cancers in women and not in men. In this report, data are presented from two independent groups of patients that suggest that the G‐allele...

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Autors principals: Bond, Gareth L, Menin, Chiara, Bertorelle, Roberta, Alhopuro, Pia, Aaltonen, Lauri A, Levine, Arnold J
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2006
Matèries:
Letter to JMG
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563203/
https://ncbi.nlm.nih.gov/pubmed/16825430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.043539
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