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A NudE/14-3-3 pathway coordinates Dynein and the Kinesin Khc73 to position the mitotic spindle

Mitotic spindle position is controlled by interactions of cortical molecular motors with astral microtubules. In animal cells, Partner of Inscuteable (Pins) acts at the cortex to coordinate the activity of Dynein and Kinesin-73 (Khc73; Kif13B in mammals) to orient the spindle. Though the two motors...

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Detalhes bibliográficos
Main Authors: Lu, Michelle S., Prehoda, Kenneth E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786870/
https://ncbi.nlm.nih.gov/pubmed/23987511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.07.021
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