P2X(7) receptor activation may be involved in neuronal loss in the retinal ganglion cell layer after acute elevation of intraocular pressure in rats

PURPOSE: To investigate whether the P2X(7) receptor is involved in retinal ganglion cell (RGC) death after the intraocular pressure (IOP) is elevated in rats. METHODS: After the IOP was elevated to 90 mmHg for 1 h, the rats were subsequently administered oxidized adenosine triphosphate (OxATP) and b...

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Main Authors: Sugiyama, Tetsuya, Lee, So Yeon, Horie, Taeko, Oku, Hidehiro, Takai, Shinji, Tanioka, Hidetoshi, Kuriki, Yumi, Kojima, Shota, Ikeda, Tsunehiko
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786454/
https://ncbi.nlm.nih.gov/pubmed/24146541
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