The RecQ helicase RECQL5 participates in psoralen-induced interstrand cross-link repair

Interstrand cross-links (ICLs) are very severe lesions as they are absolute blocks of replication and transcription. This property of interstrand cross-linking agents has been exploited clinically for the treatment of cancers and other diseases. ICLs are repaired in human cells by specialized DNA re...

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Bibliographic Details
Main Authors: Ramamoorthy, Mahesh, May, Alfred, Tadokoro, Takashi, Popuri, Venkateswarlu, Seidman, Michael M., Croteau, Deborah L., Bohr, Vilhelm A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786377/
https://ncbi.nlm.nih.gov/pubmed/23715498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt183
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