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The role of autophagy in β-cell lipotoxicity and type 2 diabetes

Autophagy, a ubiquitous catabolic pathway involved in both cell survival and cell death, has been implicated in many age-associated diseases. Recent findings have shown autophagy to be crucial for proper insulin secretion and β-cell viability. Transgenic mice lacking autophagy in their β-cells showe...

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Detalhes bibliográficos
Main Authors: Las, G., Shirihai, O.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786363/
https://ncbi.nlm.nih.gov/pubmed/21029295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1463-1326.2010.01268.x
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