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Prevalence and clinical significance of low-avidity HPA-1a antibodies in women exposed to HPA-1a during pregnancy

BACKGROUND: Recent studies suggest that HPA-1a–specific, low-avidity maternal antibodies not detectable by conventional methods can cause neonatal alloimmune thrombocytopenia (NAIT). We performed studies to further define the incidence and clinical significance of this type of antibody. STUDY DESIGN...

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Autores principales: Peterson, Julie A., Kanack, Adam, Nayak, Dhirendra, Bougie, Daniel W., McFarland, Janice G., Curtis, Brian R., Aster, Richard H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786344/
https://ncbi.nlm.nih.gov/pubmed/23003125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1537-2995.2012.03903.x
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