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Prevalence and clinical significance of low-avidity HPA-1a antibodies in women exposed to HPA-1a during pregnancy

BACKGROUND: Recent studies suggest that HPA-1a–specific, low-avidity maternal antibodies not detectable by conventional methods can cause neonatal alloimmune thrombocytopenia (NAIT). We performed studies to further define the incidence and clinical significance of this type of antibody. STUDY DESIGN...

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Detalhes bibliográficos
Main Authors: Peterson, Julie A., Kanack, Adam, Nayak, Dhirendra, Bougie, Daniel W., McFarland, Janice G., Curtis, Brian R., Aster, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786344/
https://ncbi.nlm.nih.gov/pubmed/23003125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1537-2995.2012.03903.x
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