Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes

INTRODUCTION: Tumors are characterized by alterations in the epithelial and stromal compartments, which both contribute to tumor promotion. However, where, when, and how the tumor stroma develops is still poorly understood. We previously demonstrated that DNA damage or telomere malfunction induces a...

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Main Authors: Fordyce, Colleen A, Patten, Kelley T, Fessenden, Tim B, DeFilippis, RosaAnna, Hwang, E Shelley, Zhao, Jianxin, Tlsty, Thea D
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786321/
https://ncbi.nlm.nih.gov/pubmed/23216814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3368
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