Metabolic Characterization of a Sirt5 deficient mouse model

Sirt5, localized in the mitochondria, is a member of sirtuin family of NAD(+)-dependent deacetylases. Sirt5 was shown to deacetylate and activate carbamoyl phosphate synthase 1. Most recently, Sirt5 was reported to be the predominant protein desuccinylase and demalonylase in the mitochondria because...

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Главные авторы: Yu, Jiujiu, Sadhukhan, Sushabhan, Noriega, Lilia G., Moullan, Norman, He, Bin, Weiss, Robert S., Lin, Hening, Schoonjans, Kristina, Auwerx, Johan
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786297/
https://ncbi.nlm.nih.gov/pubmed/24076663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02806
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