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Selective induction of CTL ‘helper’ rather than killer activity by natural epitope variants promotes DC-mediated HIV-1 dissemination
The ability of HIV-1 to rapidly accumulate mutations provides the virus with an effective means of escaping CD8(+) cytotoxic T lymphocyte (CTL) responses. Here we describe how subtle alterations in CTL epitopes expressed by naturally occurring HIV-1 variants can result in an incomplete escape from C...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3786204/ https://ncbi.nlm.nih.gov/pubmed/23913962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300373 |
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