Dynamic Transition States of ErbB1 Phosphorylation Predicted by Spatial Stochastic Modeling

ErbB1 overexpression is strongly linked to carcinogenesis, motivating better understanding of erbB1 dimerization and activation. Recent single-particle-tracking data have provided improved measures of dimer lifetimes and strong evidence that transient receptor coconfinement promotes repeated interac...

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Autori principali: Pryor, Meghan McCabe, Low-Nam, Shalini T., Halász, Ádám M., Lidke, Diane S., Wilson, Bridget S., Edwards, Jeremy S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2013
Soggetti:
Systems Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785885/
https://ncbi.nlm.nih.gov/pubmed/24048005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.07.056
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