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Solvation Free Energy of the Peptide Group: Its Model Dependence and Implications for the Additive-Transfer Free-Energy Model of Protein Stability

The group-additive decomposition of the unfolding free energy of a protein in an osmolyte solution relative to that in water poses a fundamental paradox: whereas the decomposition describes the experimental results rather well, theory suggests that a group-additive decomposition of free energies is,...

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Bibliografiske detaljer
Main Authors: Tomar, Dheeraj S., Asthagiri, D., Weber, Valéry
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785879/
https://ncbi.nlm.nih.gov/pubmed/24048000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.08.011
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