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Absolute Hydration Free Energies of Blocked Amino Acids: Implications for Protein Solvation and Stability

Most proteins perform their function in aqueous solution. The interactions with water determine the stability of proteins and the desolvation costs of ligand binding or membrane insertion. However, because of experimental restrictions, absolute solvation free energies of proteins or amino acids are...

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Detalhes bibliográficos
Main Authors: König, Gerhard, Bruckner, Stefan, Boresch, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552266/
https://ncbi.nlm.nih.gov/pubmed/23442867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.008
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