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Absolute Hydration Free Energies of Blocked Amino Acids: Implications for Protein Solvation and Stability
Most proteins perform their function in aqueous solution. The interactions with water determine the stability of proteins and the desolvation costs of ligand binding or membrane insertion. However, because of experimental restrictions, absolute solvation free energies of proteins or amino acids are...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552266/ https://ncbi.nlm.nih.gov/pubmed/23442867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.008 |
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