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Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia
Homocysteine is metabolized to methionine by the action of 5,10 methylenetetrahydrofolate reductase (MTHFR). Alternatively, by the transulfuration pathway, homocysteine is transformed to hydrogen sulphide (H(2)S), through multiple steps involving cystathionine β-synthase and cystathionine γ-lyase. H...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785775/ https://ncbi.nlm.nih.gov/pubmed/24019484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309049110 |
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