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Development of a histone deacetylase 6 inhibitor and its biological effects
Development of isoform-selective histone deacetylase (HDAC) inhibitors is important in elucidating the function of individual HDAC enzymes and their potential as therapeutic agents. Among the eleven zinc-dependent HDACs in humans, HDAC6 is structurally and functionally unique. Here, we show that a h...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785767/ https://ncbi.nlm.nih.gov/pubmed/24023063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313893110 |
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