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Power and Design Considerations for a General Class of Family-Based Association Tests: Quantitative Traits

In the present article, we address family-based association tests (FBATs) for quantitative traits. We propose an approach to analytical power and sample-size calculations for general FBATs; this approach can be applied to virtually any scenario (missing parental information, multiple offspring per f...

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Hlavní autoři: Lange, Christoph, DeMeo, Dawn L., Laird, Nan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC378574/
https://ncbi.nlm.nih.gov/pubmed/12454799
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