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A comparison of popular TDT-generalizations for family-based association analysis

The Transmission Disequilibrium Test (TDT) is the gold standard for testing the association between a genetic variant and disease in samples consisting of affected individuals and their parents. In practice, more complex pedigree structures, i.e., siblings with no parents, or three-generational pedi...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Hecker, Julian, Laird, Nan, Lange, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599182/
https://ncbi.nlm.nih.gov/pubmed/30609057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22181
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