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Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

Genome engineering in human pluripotent stem cells (hPSCs) holds great promise for biomedical research and regenerative medicine. Recently, an RNA-guided, DNA-cleaving interference pathway from bacteria [the type II clustered, regularly interspaced, short palindromic repeats (CRISPR)-CRISPR-associat...

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Detalhes bibliográficos
Main Authors: Hou, Zhonggang, Zhang, Yan, Propson, Nicholas E., Howden, Sara E., Chu, Li-Fang, Sontheimer, Erik J., Thomson, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785731/
https://ncbi.nlm.nih.gov/pubmed/23940360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313587110
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